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Pdc2/Pat1 increases the range of decay factors and RNA bound by the Lsm1–7 complex

Pat1, known as Pdc2 in fission yeast, promotes the activation and assembly of multiple proteins during mRNA decay. After deadenylation, the Pat1/Lsm1–7 complex binds to transcripts containing oligo(A) tails, which can be modified by the addition of several terminal uridine residues. Pat1 enhances Ls...

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Detalles Bibliográficos
Autores principales: Lobel, Joseph H., Gross, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491320/
https://www.ncbi.nlm.nih.gov/pubmed/32513655
http://dx.doi.org/10.1261/rna.075812.120