Validation strategies for antibodies targeting modified ribonucleotides

Chemical modifications are found on almost all RNAs and affect their coding and noncoding functions. The identification of m(6)A on mRNA and its important role in gene regulation stimulated the field to investigate whether additional modifications are present on mRNAs. Indeed, modifications includin...

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Detalles Bibliográficos
Autores principales: Weichmann, Franziska, Hett, Robert, Schepers, Aloys, Ito-Kureha, Taku, Flatley, Andrew, Slama, Kaouthar, Hastert, Florian D., Angstman, Nicholas B., Cardoso, M. Cristina, König, Julian, Hüttelmaier, Stefan, Dieterich, Christoph, Canzar, Stefan, Helm, Mark, Heissmeyer, Vigo, Feederle, Regina, Meister, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491328/
https://www.ncbi.nlm.nih.gov/pubmed/32636310
http://dx.doi.org/10.1261/rna.076026.120

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