Treatment strategies for asthma: reshaping the concept of asthma management

Asthma is a common chronic disease characterized by episodic or persistent respiratory symptoms and airflow limitation. Asthma treatment is based on a stepwise and control-based approach that involves an iterative cycle of assessment, adjustment of the treatment and review of the response aimed to m...

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Autores principales: Papi, Alberto, Blasi, Francesco, Canonica, Giorgio Walter, Morandi, Luca, Richeldi, Luca, Rossi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491342/
https://www.ncbi.nlm.nih.gov/pubmed/32944030
http://dx.doi.org/10.1186/s13223-020-00472-8
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author Papi, Alberto
Blasi, Francesco
Canonica, Giorgio Walter
Morandi, Luca
Richeldi, Luca
Rossi, Andrea
author_facet Papi, Alberto
Blasi, Francesco
Canonica, Giorgio Walter
Morandi, Luca
Richeldi, Luca
Rossi, Andrea
author_sort Papi, Alberto
collection PubMed
description Asthma is a common chronic disease characterized by episodic or persistent respiratory symptoms and airflow limitation. Asthma treatment is based on a stepwise and control-based approach that involves an iterative cycle of assessment, adjustment of the treatment and review of the response aimed to minimize symptom burden and risk of exacerbations. Anti-inflammatory treatment is the mainstay of asthma management. In this review we will discuss the rationale and barriers to the treatment of asthma that may result in poor outcomes. The benefits of currently available treatments and the possible strategies to overcome the barriers that limit the achievement of asthma control in real-life conditions and how these led to the GINA 2019 guidelines for asthma treatment and prevention will also be discussed.
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spelling pubmed-74913422020-09-16 Treatment strategies for asthma: reshaping the concept of asthma management Papi, Alberto Blasi, Francesco Canonica, Giorgio Walter Morandi, Luca Richeldi, Luca Rossi, Andrea Allergy Asthma Clin Immunol Review Asthma is a common chronic disease characterized by episodic or persistent respiratory symptoms and airflow limitation. Asthma treatment is based on a stepwise and control-based approach that involves an iterative cycle of assessment, adjustment of the treatment and review of the response aimed to minimize symptom burden and risk of exacerbations. Anti-inflammatory treatment is the mainstay of asthma management. In this review we will discuss the rationale and barriers to the treatment of asthma that may result in poor outcomes. The benefits of currently available treatments and the possible strategies to overcome the barriers that limit the achievement of asthma control in real-life conditions and how these led to the GINA 2019 guidelines for asthma treatment and prevention will also be discussed. BioMed Central 2020-08-15 /pmc/articles/PMC7491342/ /pubmed/32944030 http://dx.doi.org/10.1186/s13223-020-00472-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Papi, Alberto
Blasi, Francesco
Canonica, Giorgio Walter
Morandi, Luca
Richeldi, Luca
Rossi, Andrea
Treatment strategies for asthma: reshaping the concept of asthma management
title Treatment strategies for asthma: reshaping the concept of asthma management
title_full Treatment strategies for asthma: reshaping the concept of asthma management
title_fullStr Treatment strategies for asthma: reshaping the concept of asthma management
title_full_unstemmed Treatment strategies for asthma: reshaping the concept of asthma management
title_short Treatment strategies for asthma: reshaping the concept of asthma management
title_sort treatment strategies for asthma: reshaping the concept of asthma management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491342/
https://www.ncbi.nlm.nih.gov/pubmed/32944030
http://dx.doi.org/10.1186/s13223-020-00472-8
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