Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation

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Human pluripotent stem cells differentiated to insulin-secreting β Cells (SC-β Cells) in islet organoids could provide an unlimited cell source for diabetes cell replacement therapy. However, current SC-β Cells generated in vitro are transcriptionally and functionally immature compared to native adu...

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Detalles Bibliográficos
Autores principales: Augsornworawat, Punn, Maxwell, Kristina G., Velazco-Cruz, Leonardo, Millman, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491368/
https://www.ncbi.nlm.nih.gov/pubmed/32846125
http://dx.doi.org/10.1016/j.celrep.2020.108067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491368/
https://www.ncbi.nlm.nih.gov/pubmed/32846125
http://dx.doi.org/10.1016/j.celrep.2020.108067

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