Comparison of Strategies in Development and Manufacturing of Low Viscosity, Ultra-High Concentration Formulation for IgG1 Antibody

Monoclonal antibodies requiring higher doses for exerting therapeutic effect but having lower stability, are administered as dilute infusions, or as two (low concentration) injections both resulting in reduced patient compliance. Present research summarizes impact of manufacturing conditions on ultr...

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Detalles Bibliográficos
Autores principales: Deokar, Vaibhav, Sharma, Alok, Mody, Rustom, Volety, Subrahmanyam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Pharmacists Association®. Published by Elsevier Inc. 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491461/
https://www.ncbi.nlm.nih.gov/pubmed/32946895
http://dx.doi.org/10.1016/j.xphs.2020.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491461/
https://www.ncbi.nlm.nih.gov/pubmed/32946895
http://dx.doi.org/10.1016/j.xphs.2020.09.014

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