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Identifying zoonotic origin of SARS-CoV-2 by modeling the binding affinity between Spike receptor-binding domain and host ACE2
Despite considerable research progress on SARS-CoV-2, the direct zoonotic origin (intermediate host) of the virus remains ambiguous. The most definitive approach to identify the intermediate host would be the detection of SARS-CoV-2-like coronaviruses in wild animals. However, due to the high number...
Autores principales: | Huang, Xiaoqiang, Zhang, Chengxin, Pearce, Robin, Omenn, Gilbert S., Zhang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491519/ https://www.ncbi.nlm.nih.gov/pubmed/32935105 http://dx.doi.org/10.1101/2020.09.11.293449 |
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