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Identifying zoonotic origin of SARS-CoV-2 by modeling the binding affinity between Spike receptor-binding domain and host ACE2

Despite considerable research progress on SARS-CoV-2, the direct zoonotic origin (intermediate host) of the virus remains ambiguous. The most definitive approach to identify the intermediate host would be the detection of SARS-CoV-2-like coronaviruses in wild animals. However, due to the high number...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoqiang, Zhang, Chengxin, Pearce, Robin, Omenn, Gilbert S., Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491519/
https://www.ncbi.nlm.nih.gov/pubmed/32935105
http://dx.doi.org/10.1101/2020.09.11.293449

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