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Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients

Gastrointestinal bleeding due to angiodysplasia is a common problem in patients with renal insufficiency. There are several theories to explain the increased occurrence of these lesions in this specific group of patients, including various metabolic factors and existence of comorbidities. Advancemen...

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Autores principales: Verma, Sadhika, Attallah, Marline A, Jarrin Jara, Maria Daniela, Gautam, Avneesh S, Khan, Safeera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491692/
https://www.ncbi.nlm.nih.gov/pubmed/32953300
http://dx.doi.org/10.7759/cureus.9784
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author Verma, Sadhika
Attallah, Marline A
Jarrin Jara, Maria Daniela
Gautam, Avneesh S
Khan, Safeera
author_facet Verma, Sadhika
Attallah, Marline A
Jarrin Jara, Maria Daniela
Gautam, Avneesh S
Khan, Safeera
author_sort Verma, Sadhika
collection PubMed
description Gastrointestinal bleeding due to angiodysplasia is a common problem in patients with renal insufficiency. There are several theories to explain the increased occurrence of these lesions in this specific group of patients, including various metabolic factors and existence of comorbidities. Advancements made in diagnostic measures have helped route the approach in patients with different risk factors and have also helped solve the dual purpose involving therapeutic intervention with endoscopy. We conducted a thorough literature search on PubMed to extract relevant data. A total of 29 articles were chosen after applying the inclusion and exclusion criteria. Although the clinical presentations may vary in this cohort of patients, and bleeding is known to stop spontaneously, a conservative approach may not be enough. Endoscopic treatment, use of hormones like estrogen, octreotide, and vasopressin, arterial embolization, and lastly surgery are valuable therapeutic tools.
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spelling pubmed-74916922020-09-17 Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients Verma, Sadhika Attallah, Marline A Jarrin Jara, Maria Daniela Gautam, Avneesh S Khan, Safeera Cureus Internal Medicine Gastrointestinal bleeding due to angiodysplasia is a common problem in patients with renal insufficiency. There are several theories to explain the increased occurrence of these lesions in this specific group of patients, including various metabolic factors and existence of comorbidities. Advancements made in diagnostic measures have helped route the approach in patients with different risk factors and have also helped solve the dual purpose involving therapeutic intervention with endoscopy. We conducted a thorough literature search on PubMed to extract relevant data. A total of 29 articles were chosen after applying the inclusion and exclusion criteria. Although the clinical presentations may vary in this cohort of patients, and bleeding is known to stop spontaneously, a conservative approach may not be enough. Endoscopic treatment, use of hormones like estrogen, octreotide, and vasopressin, arterial embolization, and lastly surgery are valuable therapeutic tools. Cureus 2020-08-16 /pmc/articles/PMC7491692/ /pubmed/32953300 http://dx.doi.org/10.7759/cureus.9784 Text en Copyright © 2020, Verma et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Verma, Sadhika
Attallah, Marline A
Jarrin Jara, Maria Daniela
Gautam, Avneesh S
Khan, Safeera
Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title_full Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title_fullStr Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title_full_unstemmed Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title_short Angiodysplasia in Renal Disease Patients: Analysis of Risk Factors and Approach to Manage Such Patients
title_sort angiodysplasia in renal disease patients: analysis of risk factors and approach to manage such patients
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491692/
https://www.ncbi.nlm.nih.gov/pubmed/32953300
http://dx.doi.org/10.7759/cureus.9784
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