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Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AN...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491759/ https://www.ncbi.nlm.nih.gov/pubmed/32984132 http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20 |
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author | Jaseem, Muhammed Alungal, Shana Dhiyaneswaran, Shamsudeen, Jaseem |
author_facet | Jaseem, Muhammed Alungal, Shana Dhiyaneswaran, Shamsudeen, Jaseem |
author_sort | Jaseem, Muhammed |
collection | PubMed |
description | CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AND DESIGN: A retrospective descriptive study from previous case records of chronic nonhealing ulcer patients who were treated with autologous PRP therapy at a specialty orthopedic hospital from September 2017 to August 2019. METHODS AND MATERIALS: Data on patients who presented with chronic nonhealing ulcers of >4 weeks duration who were treated with autologous PRP therapy and followed up for 20 weeks. STATISTICAL ANALYSIS USED: Statistical Package for the Social Sciences (SPSS) version 20 was used to calculate mean. Microsoft Excel was used for preparing the chart. RESULTS: The mean age of patients treated with autologous PRP therapy was 61.24 years, and the follow-up period was 20 weeks. The mean duration of ulcer healing following PRP therapy was 11.25 weeks, 80% of the patient showed ulcer size reduction of >75% following therapy. CONCLUSIONS: In this retrospective descriptive study, it has demonstrated the effectiveness and safety of autologous PRP therapy in the healing of chronic nonhealing ulcers. |
format | Online Article Text |
id | pubmed-7491759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-74917592020-09-24 Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study Jaseem, Muhammed Alungal, Shana Dhiyaneswaran, Shamsudeen, Jaseem J Family Med Prim Care Original Article CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AND DESIGN: A retrospective descriptive study from previous case records of chronic nonhealing ulcer patients who were treated with autologous PRP therapy at a specialty orthopedic hospital from September 2017 to August 2019. METHODS AND MATERIALS: Data on patients who presented with chronic nonhealing ulcers of >4 weeks duration who were treated with autologous PRP therapy and followed up for 20 weeks. STATISTICAL ANALYSIS USED: Statistical Package for the Social Sciences (SPSS) version 20 was used to calculate mean. Microsoft Excel was used for preparing the chart. RESULTS: The mean age of patients treated with autologous PRP therapy was 61.24 years, and the follow-up period was 20 weeks. The mean duration of ulcer healing following PRP therapy was 11.25 weeks, 80% of the patient showed ulcer size reduction of >75% following therapy. CONCLUSIONS: In this retrospective descriptive study, it has demonstrated the effectiveness and safety of autologous PRP therapy in the healing of chronic nonhealing ulcers. Wolters Kluwer - Medknow 2020-06-30 /pmc/articles/PMC7491759/ /pubmed/32984132 http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Jaseem, Muhammed Alungal, Shana Dhiyaneswaran, Shamsudeen, Jaseem Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title | Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title_full | Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title_fullStr | Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title_full_unstemmed | Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title_short | Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study |
title_sort | effectiveness of autologous prp therapy in chronic nonhealing ulcer: a 2-year retrospective descriptive study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491759/ https://www.ncbi.nlm.nih.gov/pubmed/32984132 http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20 |
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