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Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study

CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AN...

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Autores principales: Jaseem, Muhammed, Alungal, Shana, Dhiyaneswaran, Shamsudeen, Jaseem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491759/
https://www.ncbi.nlm.nih.gov/pubmed/32984132
http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20
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author Jaseem, Muhammed
Alungal, Shana
Dhiyaneswaran,
Shamsudeen, Jaseem
author_facet Jaseem, Muhammed
Alungal, Shana
Dhiyaneswaran,
Shamsudeen, Jaseem
author_sort Jaseem, Muhammed
collection PubMed
description CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AND DESIGN: A retrospective descriptive study from previous case records of chronic nonhealing ulcer patients who were treated with autologous PRP therapy at a specialty orthopedic hospital from September 2017 to August 2019. METHODS AND MATERIALS: Data on patients who presented with chronic nonhealing ulcers of >4 weeks duration who were treated with autologous PRP therapy and followed up for 20 weeks. STATISTICAL ANALYSIS USED: Statistical Package for the Social Sciences (SPSS) version 20 was used to calculate mean. Microsoft Excel was used for preparing the chart. RESULTS: The mean age of patients treated with autologous PRP therapy was 61.24 years, and the follow-up period was 20 weeks. The mean duration of ulcer healing following PRP therapy was 11.25 weeks, 80% of the patient showed ulcer size reduction of >75% following therapy. CONCLUSIONS: In this retrospective descriptive study, it has demonstrated the effectiveness and safety of autologous PRP therapy in the healing of chronic nonhealing ulcers.
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spelling pubmed-74917592020-09-24 Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study Jaseem, Muhammed Alungal, Shana Dhiyaneswaran, Shamsudeen, Jaseem J Family Med Prim Care Original Article CONTEXT: Chronic nonhealing ulcer is a troublesome condition in patients especially with diabetes. Autologous PRP therapy can safely and effectively heal a chronic nonhealing ulcer in such patients. AIMS: To study the effectiveness of autologous PRP therapy in a chronic nonhealing ulcer. SETTINGS AND DESIGN: A retrospective descriptive study from previous case records of chronic nonhealing ulcer patients who were treated with autologous PRP therapy at a specialty orthopedic hospital from September 2017 to August 2019. METHODS AND MATERIALS: Data on patients who presented with chronic nonhealing ulcers of >4 weeks duration who were treated with autologous PRP therapy and followed up for 20 weeks. STATISTICAL ANALYSIS USED: Statistical Package for the Social Sciences (SPSS) version 20 was used to calculate mean. Microsoft Excel was used for preparing the chart. RESULTS: The mean age of patients treated with autologous PRP therapy was 61.24 years, and the follow-up period was 20 weeks. The mean duration of ulcer healing following PRP therapy was 11.25 weeks, 80% of the patient showed ulcer size reduction of >75% following therapy. CONCLUSIONS: In this retrospective descriptive study, it has demonstrated the effectiveness and safety of autologous PRP therapy in the healing of chronic nonhealing ulcers. Wolters Kluwer - Medknow 2020-06-30 /pmc/articles/PMC7491759/ /pubmed/32984132 http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jaseem, Muhammed
Alungal, Shana
Dhiyaneswaran,
Shamsudeen, Jaseem
Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title_full Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title_fullStr Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title_full_unstemmed Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title_short Effectiveness of autologous PRP therapy in chronic nonhealing ulcer: A 2-year retrospective descriptive study
title_sort effectiveness of autologous prp therapy in chronic nonhealing ulcer: a 2-year retrospective descriptive study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491759/
https://www.ncbi.nlm.nih.gov/pubmed/32984132
http://dx.doi.org/10.4103/jfmpc.jfmpc_177_20
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