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Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India

BACKGROUND: Leprosy is a chronic granulomatous infectious disease, which mainly involves skin, peripheral nerves, mucosa of the upper respiratory tract, and eyes. According to National Leprosy Eradication Programme 2017–18 annual report, the annual new case detection rate from Rajasthan is 1.27 per...

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Autores principales: Kalita, Jitu Mani, Nag, Vijaya Lakshmi, Yedale, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491769/
https://www.ncbi.nlm.nih.gov/pubmed/32984125
http://dx.doi.org/10.4103/jfmpc.jfmpc_77_20
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author Kalita, Jitu Mani
Nag, Vijaya Lakshmi
Yedale, Kavita
author_facet Kalita, Jitu Mani
Nag, Vijaya Lakshmi
Yedale, Kavita
author_sort Kalita, Jitu Mani
collection PubMed
description BACKGROUND: Leprosy is a chronic granulomatous infectious disease, which mainly involves skin, peripheral nerves, mucosa of the upper respiratory tract, and eyes. According to National Leprosy Eradication Programme 2017–18 annual report, the annual new case detection rate from Rajasthan is 1.27 per 1 lakh population and prevalence rate is 0.14. AIMS AND OBJECTIVE: The main objective of this study was to determine the spectrum of Mycobacterium leprae infections among suspected cases attending a teaching hospital in western Rajasthan, India. MATERIALS AND METHODS: This is a retrospective study conducted in the Department of Microbiology, in a teaching hospital, western Rajasthan, between the period of January 2017 and April 2019. The records of modified Ziehl–Neelsen staining during the study period were analyzed. The demographic data like age and sex along with clinical diagnosis were also recorded from laboratory register and hospital information system. RESULTS: Out of total 91 suspected cases, 30.77% was microbiologically confirmed cases of leprosy. Out of total positive cases, 71.43% were male and 28.57% were female. A maximum number of positive (50%) were found in the age group of 31–50 years. CONCLUSION: Present study gives an insight about the spectrum of leprosy in the region. The large number of positive cases signifies that leprosy awareness and programs aimed at elimination need to be more vigorously implemented. To achieve complete eradication from this menace, newer strategies like effective vaccine development and drug-resistance testing should be implemented.
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spelling pubmed-74917692020-09-24 Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India Kalita, Jitu Mani Nag, Vijaya Lakshmi Yedale, Kavita J Family Med Prim Care Original Article BACKGROUND: Leprosy is a chronic granulomatous infectious disease, which mainly involves skin, peripheral nerves, mucosa of the upper respiratory tract, and eyes. According to National Leprosy Eradication Programme 2017–18 annual report, the annual new case detection rate from Rajasthan is 1.27 per 1 lakh population and prevalence rate is 0.14. AIMS AND OBJECTIVE: The main objective of this study was to determine the spectrum of Mycobacterium leprae infections among suspected cases attending a teaching hospital in western Rajasthan, India. MATERIALS AND METHODS: This is a retrospective study conducted in the Department of Microbiology, in a teaching hospital, western Rajasthan, between the period of January 2017 and April 2019. The records of modified Ziehl–Neelsen staining during the study period were analyzed. The demographic data like age and sex along with clinical diagnosis were also recorded from laboratory register and hospital information system. RESULTS: Out of total 91 suspected cases, 30.77% was microbiologically confirmed cases of leprosy. Out of total positive cases, 71.43% were male and 28.57% were female. A maximum number of positive (50%) were found in the age group of 31–50 years. CONCLUSION: Present study gives an insight about the spectrum of leprosy in the region. The large number of positive cases signifies that leprosy awareness and programs aimed at elimination need to be more vigorously implemented. To achieve complete eradication from this menace, newer strategies like effective vaccine development and drug-resistance testing should be implemented. Wolters Kluwer - Medknow 2020-06-30 /pmc/articles/PMC7491769/ /pubmed/32984125 http://dx.doi.org/10.4103/jfmpc.jfmpc_77_20 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kalita, Jitu Mani
Nag, Vijaya Lakshmi
Yedale, Kavita
Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title_full Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title_fullStr Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title_full_unstemmed Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title_short Spectrum of leprosy among suspected cases attending a teaching hospital in Western Rajasthan, India
title_sort spectrum of leprosy among suspected cases attending a teaching hospital in western rajasthan, india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491769/
https://www.ncbi.nlm.nih.gov/pubmed/32984125
http://dx.doi.org/10.4103/jfmpc.jfmpc_77_20
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