Selection of Macrolide and Non-Macrolide Resistance with Mass Azithromycin Distribution: A Community-Randomized Trial

BACKGROUND: Biannual mass azithromycin distributions to preschool children for 2 years have been shown to reduce childhood mortality in sub-Saharan Africa, but at the cost of amplifying macrolide resistance. Here we investigated the gut resistome of children after 4 additional biannual distributions...

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Detalles Bibliográficos
Autores principales: Doan, Thuy, Worden, Lee, Hinterwirth, Armin, Arzika, Ahmed M., Maliki, Ramatou, Abdou, Amza, Zhong, Lina, Chen, Cindi, Cook, Catherine, Lebas, Elodie, O’Brien, Kieran S., Oldenburg, Catherine E., Chow, Eric D., Porco, Travis C., Lipsitch, Marc, Keenan, Jeremy D., Lietman, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492079/
https://www.ncbi.nlm.nih.gov/pubmed/33176084
http://dx.doi.org/10.1056/NEJMoa2002606

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