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Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19

The Polycomb repressive complex 2 (PRC2) is a multicomponent histone H3K27 methyltransferase complex, best known for silencing the Hox genes during embryonic development. The Polycomb-like proteins PHF1, MTF2, and PHF19 are critical components of PRC2 by stimulating its catalytic activity in embryon...

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Detalles Bibliográficos
Autores principales:	Dong, Cheng, Nakagawa, Reiko, Oyama, Kyohei, Yamamoto, Yusuke, Zhang, Weilian, Dong, Aiping, Li, Yanjun, Yoshimura, Yuriko, Kamiya, Hiroyuki, Nakayama, Jun-ichi, Ueda, Jun, Min, Jinrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492083/ https://www.ncbi.nlm.nih.gov/pubmed/32869745 http://dx.doi.org/10.7554/eLife.58675

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