Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3

In addition to extruding DNA loops, cohesin entraps within its SMC-kleisin ring (S-K) individual DNAs during G1 and sister DNAs during S-phase. All three activities require related hook-shaped proteins called Scc2 and Scc3. Using thiol-specific crosslinking we provide rigorous proof of entrapment ac...

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Detalles Bibliográficos
Autores principales: Collier, James E, Lee, Byung-Gil, Roig, Maurici Brunet, Yatskevich, Stanislav, Petela, Naomi J, Metson, Jean, Voulgaris, Menelaos, Gonzalez Llamazares, Andres, Löwe, Jan, Nasmyth, Kim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492086/
https://www.ncbi.nlm.nih.gov/pubmed/32930661
http://dx.doi.org/10.7554/eLife.59560

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