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Chloroquine against malaria, cancers and viral diseases
Quinoline (QN) derivatives are often used for the prophylaxis and treatment of malaria. Chloroquine (CQ), a protonated, weakly basic drug, exerts its antimalarial effect mainly by increasing pH and accumulating in the food vacuole of the parasites. Repurposing CQ is an emerging strategy for new indi...
Autores principales: | Zhou, Wenmin, Wang, Hui, Yang, Yuqi, Chen, Zhe-Sheng, Zou, Chang, Zhang, Jianye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492153/ https://www.ncbi.nlm.nih.gov/pubmed/32947043 http://dx.doi.org/10.1016/j.drudis.2020.09.010 |
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