Linc-RA1 inhibits autophagy and promotes radioresistance by preventing H2Bub1/USP44 combination in glioma cells

Radiotherapy is one of the standard treatments for glioma patients; however, its clinical efficacy is limited by radioresistance. We identified a mechanism of such resistance mediated by linc-RA1 (radioresistance-associated long intergenic noncoding RNA 1). Linc-RA1 was upregulated in radioresistant...

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Detalles Bibliográficos
Autores principales: Zheng, Jieling, Wang, Baiyao, Zheng, Rong, Zhang, Jian, Huang, Chunyue, Zheng, Ronghui, Huang, Zhong, Qiu, Wenze, Liu, Mengzhong, Yang, Kaijun, Mao, Zixu, Ji, Aimin, Yuan, Yawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492255/
https://www.ncbi.nlm.nih.gov/pubmed/32934196
http://dx.doi.org/10.1038/s41419-020-02977-x

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