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Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy

The ubiquitin–proteasome system has the capacity to degrade polyubiquitinated proteins and plays an important role in many cellular processes. However, the role of Rpt3, a crucial proteasomal gene, has not been investigated in adult muscles in vivo. Herein, we generated skeletal-muscle-specific Rpt3...

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Detalles Bibliográficos
Autores principales: Kitajima, Yasuo, Suzuki, Naoki, Yoshioka, Kiyoshi, Izumi, Rumiko, Tateyama, Maki, Tashiro, Yoshitaka, Takahashi, Ryosuke, Aoki, Masashi, Ono, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492297/
https://www.ncbi.nlm.nih.gov/pubmed/32984340
http://dx.doi.org/10.3389/fcell.2020.00859