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In silico design and molecular docking study of CDK2 inhibitors with potent cytotoxic activity against HCT116 colorectal cancer cell line
BACKGROUND: Colorectal cancer is common to both sexes; third in terms of morbidity and second in terms of mortality, accounting for 10% and 9.2% of cancer cases in men and women globally. Although drugs such as bevacizumab, Camptosar, and cetuximab are being used to manage colorectal cancer, the eff...
Autores principales: | Ikwu, Fabian Adakole, Isyaku, Yusuf, Obadawo, Babatunde Samuel, Lawal, Hadiza Abdulrahman, Ajibowu, Samuel Akolade |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492310/ https://www.ncbi.nlm.nih.gov/pubmed/32930901 http://dx.doi.org/10.1186/s43141-020-00066-2 |
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