IGF2BP3 May Contributes to Lung Tumorigenesis by Regulating the Alternative Splicing of PKM

RNA binding proteins (RBPs) play a key role in genome regulation. Here we report the post-transcript regulation of IGF2BP3, which belongs to the insulin-like growth factor 2 mRNA binding protein family. We used iRIP-seq and RNA-seq to analyze the transcript regulation and alternative splicing on IGF...

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Detalles Bibliográficos
Autores principales: Xueqing, Huang, Jun, Zhang, Yueqiang, Jiang, Xin, Liao, Liya, Hu, Yuanyuan, Fang, Yuting, Zhang, Hao, Zeng, Hua, Wu, Jian, Liu, Tiejun, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492387/
https://www.ncbi.nlm.nih.gov/pubmed/32984260
http://dx.doi.org/10.3389/fbioe.2020.00679

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