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Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis

PURPOSE: The Toll-like receptor 9 (TLR9) signaling pathway is involved in the pathogenesis of chronic rhinosinusitis (CRS) with nasal polyposis. The aim of this study was to assess the therapeutic potential of the TLR9 pathway inhibitor chloroquine in CRS mice. METHODS: The expression of type I inte...

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Detalles Bibliográficos
Autores principales:	Choi, Mi-Ra, Xu, Jun, Lee, Seulgi, Yeon, Sun-Hee, Park, Soo-Kyoung, Rha, Ki-Sang, Kim, Yong Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492509/ https://www.ncbi.nlm.nih.gov/pubmed/32935491 http://dx.doi.org/10.4168/aair.2020.12.6.994

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