Cargando…

Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients

Initially underestimated as platelet dust, extracellular vesicles are continuously gaining interest in the field of inflammation. Various studies addressing inflammatory diseases have shown that microvesicles (MVs) originating from different cell types are systemic transport vehicles carrying distin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karasu, Ebru, Demmelmaier, Julia, Kellermann, Stephanie, Holzmann, Karlheinz, Köhl, Jörg, Schmidt, Christoph Q., Kalbitz, Miriam, Gebhard, Florian, Huber-Lang, Markus S., Halbgebauer, Rebecca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492592/ https://www.ncbi.nlm.nih.gov/pubmed/32983087 http://dx.doi.org/10.3389/fimmu.2020.01789

Ejemplares similares

Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI)
por: Kalbitz, Miriam, et al.
Publicado: (2016)

Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction
por: Karasu, Ebru, et al.
Publicado: (2019)

Corrigendum: Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction
por: Karasu, Ebru, et al.
Publicado: (2019)

Biology and biogenesis of shed microvesicles
por: Tricarico, Christopher, et al.
Publicado: (2016)

Complement After Trauma: Suturing Innate and Adaptive Immunity
por: Chakraborty, Shinjini, et al.
Publicado: (2018)

Extracellular Vesicles: Packages Sent With Complement
por: Karasu, Ebru, et al.
Publicado: (2018)

Inflammatory Changes and Coagulopathy in Multiply Injured Patients
por: Huber-Lang, Markus, et al.
Publicado: (2015)

Complement Factor C5a Inhibits Apoptosis of Neutrophils—A Mechanism in Polytrauma?
por: Ehrnthaller, Christian, et al.
Publicado: (2021)

Alteration of complement hemolytic activity in different trauma and sepsis models
por: Ehrnthaller, Christian, et al.
Publicado: (2012)

Early structural changes of the heart after experimental polytrauma and hemorrhagic shock
por: Braun, Christian K., et al.
Publicado: (2017)

CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner
por: Zeller, Johannes, et al.
Publicado: (2021)

Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma
por: Seibold, Tanja, et al.
Publicado: (2021)

Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury
por: Debler, Lisa, et al.
Publicado: (2021)

Complement Activation and Organ Damage After Trauma—Differential Immune Response Based on Surgical Treatment Strategy
por: Lackner, Ina, et al.
Publicado: (2020)

Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe’s disease
por: D’Auria, Ludovic, et al.
Publicado: (2017)

Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis
por: Lackner, Ina, et al.
Publicado: (2020)

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity
por: Lo Cicero, Alessandra, et al.
Publicado: (2012)

Coxsackievirus B Exits the Host Cell in Shed Microvesicles Displaying Autophagosomal Markers
por: Robinson, Scott M., et al.
Publicado: (2014)

Recent Insights into Human Endometrial Peptidases in Blastocyst Implantation via Shedding of Microvesicles
por: Yoshihara, Masato, et al.
Publicado: (2021)

Increased Presence of Complement Factors and Mast Cells in Alveolar Bone and Tooth Resorption
por: Luntzer, Kathrin, et al.
Publicado: (2021)

The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding
por: Mouasni, Sara, et al.
Publicado: (2019)

New Insights of an Old Defense System: Structure, Function, and Clinical Relevance of the Complement System
por: Ehrnthaller, Christian, et al.
Publicado: (2011)

Platelet-Derived Microvesicles in Cardiovascular Diseases
por: Zaldivia, Maria T. K., et al.
Publicado: (2017)

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock
por: Halbgebauer, Rebecca, et al.
Publicado: (2020)

Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane
Publicado: (1990)

Distinct shed microvesicle and exosome microRNA signatures reveal diagnostic markers for colorectal cancer
por: Chen, Maoshan, et al.
Publicado: (2019)

Microvesicles shed from fibroblasts act as metalloproteinase carriers in a 3-D collagen matrix
por: Laghezza Masci, Valentina, et al.
Publicado: (2016)

Porphyromonas gingivalis triggers the shedding of inflammatory endothelial microvesicles that act as autocrine effectors of endothelial dysfunction
por: Bugueno, Isaac Maximiliano, et al.
Publicado: (2020)

Neurochemical Monitoring of Traumatic Brain Injury by the Combined Analysis of Plasma Beta-Synuclein, NfL, and GFAP in Polytraumatized Patients
por: Halbgebauer, Rebecca, et al.
Publicado: (2022)

Extracellular microvesicles promote microglia‐mediated pro‐inflammatory responses to ethanol
por: Crews, Fulton T., et al.
Publicado: (2021)

Deficiency of DICER reduces the invasion ability of trophoblasts and impairs the pro‐angiogenic effect of trophoblast‐derived microvesicles
por: Tang, Li, et al.
Publicado: (2020)

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients
por: Rahbar, Elaheh, et al.
Publicado: (2015)

Mast cells secrete IL-15 by microvesicles shedding upon P2X7 receptor stimulation
por: Bulanova, E, et al.
Publicado: (2009)

Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death
por: Beneventano, Martina, et al.
Publicado: (2017)

Cardiomyocyte microvesicles: proinflammatory mediators after myocardial ischemia?
por: Siegel, Patrick Malcolm, et al.
Publicado: (2020)

Attack of the microvesicles
por: Wells, William A.
Publicado: (2002)

Tackling COVID‐19 infection through complement‐targeted immunotherapy
por: Jodele, Sonata, et al.
Publicado: (2020)

Microvesicle Shedding and Lysosomal Repair Fulfill Divergent Cellular Needs during the Repair of Streptolysin O-Induced Plasmalemmal Damage
por: Atanassoff, Alexander P., et al.
Publicado: (2014)

Trauma, a Matter of the Heart—Molecular Mechanism of Post-Traumatic Cardiac Dysfunction
por: Weber, Birte, et al.
Publicado: (2021)

Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis
por: Bülow, Jasmin Maria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_067egm4qjpvtbqqpl2cfejgtpb