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Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP

Zika virus (ZIKV) infection during pregnancy causes intrauterine growth defects and microcephaly, but knowledge of the mechanism through which ZIKV infects and replicates in the placenta remains elusive. Here, we found that ALPP, an alkaline phosphatase expressed primarily in placental tissue, promo...

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Detalles Bibliográficos
Autores principales:	Chen, Jian, Chen, Zhilu, Liu, Mingbin, Qiu, Tianyi, Feng, Daobin, Zhao, Chen, Zhang, Shuye, Zhang, Xiaoyan, Xu, Jianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492734/ https://www.ncbi.nlm.nih.gov/pubmed/32934082 http://dx.doi.org/10.1128/mBio.01716-20

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