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Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals

Modulation of cortical beta rhythm (15–30 Hz) is present during preparation for and execution of voluntary movements as well as during somatosensory stimulation. A rebound in beta synchronization is observed after the end of voluntary movements as well as after somatosensory stimulation and is belie...

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Autores principales: Cardellicchio, Pasquale, Hilt, Pauline M., Dolfini, Elisa, Fadiga, Luciano, D’Ausilio, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492746/
https://www.ncbi.nlm.nih.gov/pubmed/32982705
http://dx.doi.org/10.3389/fnsys.2020.00063
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author Cardellicchio, Pasquale
Hilt, Pauline M.
Dolfini, Elisa
Fadiga, Luciano
D’Ausilio, Alessandro
author_facet Cardellicchio, Pasquale
Hilt, Pauline M.
Dolfini, Elisa
Fadiga, Luciano
D’Ausilio, Alessandro
author_sort Cardellicchio, Pasquale
collection PubMed
description Modulation of cortical beta rhythm (15–30 Hz) is present during preparation for and execution of voluntary movements as well as during somatosensory stimulation. A rebound in beta synchronization is observed after the end of voluntary movements as well as after somatosensory stimulation and is believed to describe the return to baseline of sensorimotor networks. However, the contribution of efferent and afferent signals to the beta rebound remains poorly understood. Here, we applied electrical median nerve stimulation (MNS) to the right side followed by transcranial magnetic stimulation (TMS) on the left primary motor cortex after either 15 or 25 ms. Because the afferent volley reaches the somatosensory cortex after about 20 ms, TMS on the motor cortex was either anticipating or following the cortical arrival of the peripheral stimulus. We show modulations in different beta sub-bands and in both hemispheres, following a pattern of greater resynchronization when motor signals are paired with a peripheral one. The beta rebound in the left hemisphere (stimulated) is modulated in its lower frequency range when TMS precedes the cortical arrival of the afferent volley. In the right hemisphere (unstimulated), instead, the increase is limited to higher beta frequencies when TMS is delivered after the arrival of the afferent signal. In general, we demonstrate that the temporal integration of afferent and efferent signals plays a key role in the genesis of the beta rebound and that these signals may be carried in parallel by different beta sub-bands.
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spelling pubmed-74927462020-09-24 Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals Cardellicchio, Pasquale Hilt, Pauline M. Dolfini, Elisa Fadiga, Luciano D’Ausilio, Alessandro Front Syst Neurosci Neuroscience Modulation of cortical beta rhythm (15–30 Hz) is present during preparation for and execution of voluntary movements as well as during somatosensory stimulation. A rebound in beta synchronization is observed after the end of voluntary movements as well as after somatosensory stimulation and is believed to describe the return to baseline of sensorimotor networks. However, the contribution of efferent and afferent signals to the beta rebound remains poorly understood. Here, we applied electrical median nerve stimulation (MNS) to the right side followed by transcranial magnetic stimulation (TMS) on the left primary motor cortex after either 15 or 25 ms. Because the afferent volley reaches the somatosensory cortex after about 20 ms, TMS on the motor cortex was either anticipating or following the cortical arrival of the peripheral stimulus. We show modulations in different beta sub-bands and in both hemispheres, following a pattern of greater resynchronization when motor signals are paired with a peripheral one. The beta rebound in the left hemisphere (stimulated) is modulated in its lower frequency range when TMS precedes the cortical arrival of the afferent volley. In the right hemisphere (unstimulated), instead, the increase is limited to higher beta frequencies when TMS is delivered after the arrival of the afferent signal. In general, we demonstrate that the temporal integration of afferent and efferent signals plays a key role in the genesis of the beta rebound and that these signals may be carried in parallel by different beta sub-bands. Frontiers Media S.A. 2020-09-02 /pmc/articles/PMC7492746/ /pubmed/32982705 http://dx.doi.org/10.3389/fnsys.2020.00063 Text en Copyright © 2020 Cardellicchio, Hilt, Dolfini, Fadiga and D’Ausilio. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Cardellicchio, Pasquale
Hilt, Pauline M.
Dolfini, Elisa
Fadiga, Luciano
D’Ausilio, Alessandro
Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title_full Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title_fullStr Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title_full_unstemmed Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title_short Beta Rebound as an Index of Temporal Integration of Somatosensory and Motor Signals
title_sort beta rebound as an index of temporal integration of somatosensory and motor signals
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492746/
https://www.ncbi.nlm.nih.gov/pubmed/32982705
http://dx.doi.org/10.3389/fnsys.2020.00063
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