Macrophage membrane-coated nanocarriers Co-Modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimer's disease mice

Neuronal mitochondrial dysfunction caused by excessive reactive oxygen species (ROS) is an early event of sporadic Alzheimer's disease (AD), and considered to be a key pathologic factor in the progression of AD. The targeted delivery of the antioxidants to mitochondria of injured neurons in bra...

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Detalles Bibliográficos
Autores principales: Han, Yang, Gao, Chunhong, Wang, Hao, Sun, Jiejie, Liang, Meng, Feng, Ye, Liu, Qianqian, Fu, Shiyao, Cui, Lin, Gao, Chunsheng, Li, Yi, Yang, Yang, Sun, Baoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492821/
https://www.ncbi.nlm.nih.gov/pubmed/32995678
http://dx.doi.org/10.1016/j.bioactmat.2020.08.017

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