A Sphingosine-1-Phosphate Receptor Modulator Attenuated Secondary Brain Injury and Improved Neurological Functions of Mice after ICH

BACKGROUND: Stroke activates the immune system and induces brain infiltration by immune cells, aggravating brain injury. Poststroke immunomodulation via (S1P-)receptor modulation is beneficial; however, the S1P-modulator in clinical use (FTY-720) is unspecific, and undesirable side effects have been...

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Detalles Bibliográficos
Autores principales: Bobinger, T., Bäuerle, T., Seyler, L., v Horsten, S., Schwab, S., Huttner, H. B., Manaenko, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492867/
https://www.ncbi.nlm.nih.gov/pubmed/32963692
http://dx.doi.org/10.1155/2020/3214350

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