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Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy

Spinal cord injury (SCI) is a destructive neurological disorder that is characterized by impaired sensory and motor function. Inhibition of bromodomain protein 4 (Brd4) has been shown to promote the maintenance of cell homeostasis by activating autophagy. However, the role of Brd4 inhibition in SCI...

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Detalles Bibliográficos
Autores principales: Li, Yao, Xiang, Jie, Zhang, Jing, Lin, Jiahao, Wu, Yaosen, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493001/
https://www.ncbi.nlm.nih.gov/pubmed/32982695
http://dx.doi.org/10.3389/fncel.2020.555591