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Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy
Spinal cord injury (SCI) is a destructive neurological disorder that is characterized by impaired sensory and motor function. Inhibition of bromodomain protein 4 (Brd4) has been shown to promote the maintenance of cell homeostasis by activating autophagy. However, the role of Brd4 inhibition in SCI...
Autores principales: | Li, Yao, Xiang, Jie, Zhang, Jing, Lin, Jiahao, Wu, Yaosen, Wang, Xiangyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493001/ https://www.ncbi.nlm.nih.gov/pubmed/32982695 http://dx.doi.org/10.3389/fncel.2020.555591 |
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