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Cofactor Generation Cascade for α-Ketoglutarate and Fe(II)-Dependent Dioxygenases

[Image: see text] Fe(II)- and α-ketoglutarate dependent dioxygenases have emerged as important catalysts for the preparation of non-natural amino acids. The stoichiometric supply of the cosubstrate α-ketoglutarate (αKG) is an important cost factor. A combination of the N-succinyl amino acid hydroxyl...

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Detalles Bibliográficos
Autores principales:	Busch, Florian, Brummund, Jan, Calderini, Elia, Schürmann, Martin, Kourist, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493210/ https://www.ncbi.nlm.nih.gov/pubmed/32953283 http://dx.doi.org/10.1021/acssuschemeng.0c01122

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