Cargando…

EGFR/c-Met and mTOR signaling are predictors of survival in non-small cell lung cancer

BACKGROUND: EGFR/c-Met activation/amplification and co-expression, mTOR upregulation/activation, and Akt/Wnt signaling upregulation have been individually associated with more aggressive disease and characterized as potential prognostic markers for lung cancer patients. METHODS: Tumors obtained from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crees, Zachary D, Shearrow, Caleb, Lin, Leo, Girard, Jennifer, Arasi, Kavin, Bhoraskar, Aayush, Berei, Joseph, Eckburg, Adam, Anderson, Austin D., Garcia, Christian, Munger, Ariana, Palani, Sunil, Smith, Thomas J, Sreenivassappa, Shylendra B, Vitali, Connie, David, Odile, Puri, Neelu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Advances in Treatment of Lung Cancer Patients with Targetable Mutations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493230/ https://www.ncbi.nlm.nih.gov/pubmed/32973931 http://dx.doi.org/10.1177/1758835920953731

Ejemplares similares

Hypothesis generative head-to-head study comparing efficacy of afatinib and osimertinib based on immunological biomarkers in Japanese NSCLC patients with EGFR mutations (Heat on Beat study)
por: Morikawa, Kei, et al.
Publicado: (2020)

The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation
por: Wu, Shang-Gin, et al.
Publicado: (2020)

Bayesian network meta-analysis of efficacy and safety of neoadjuvant therapy for non-small-cell lung cancer
por: Ren, Yijiu, et al.
Publicado: (2020)

Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program
por: Frost, Nikolaj, et al.
Publicado: (2021)

Selpercatinib in RET fusion-positive non-small-cell lung cancer (SIREN): a retrospective analysis of patients treated through an access program
por: Illini, Oliver, et al.
Publicado: (2021)

Systemic therapy in metastatic pancreatic adenocarcinoma: current practice and perspectives
por: Lellouche, Lisa, et al.
Publicado: (2021)

The relative importance of predictive factors for single first-generation EGFR-TKI use for more than 5 years in patients with advanced non-small cell lung cancer: Taiwan multicenter TIPS-5 study
por: Huang, Yen-Hsiang, et al.
Publicado: (2021)

Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer
por: Osude, Chike, et al.
Publicado: (2022)

Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy
por: Eckburg, Adam, et al.
Publicado: (2020)

Identification of an unknown frameshift variant of NOG in a Han Chinese family with proximal symphalangism
por: Yuan, Zhuang-Zhuang, et al.
Publicado: (2020)

Identification of a frame shift mutation in the CCDC151 gene in a Han-Chinese family with Kartagener syndrome
por: Deng, Sheng, et al.
Publicado: (2020)

The association between Interleukin-6 rs1800795/rs1800797 polymorphisms and risk of rotator cuff tear in a Chinese population
por: Li, Jin, et al.
Publicado: (2020)

Reply to comments on: “Obesity associated with a novel mitochondrial tRNA(Cys) 5802A>G mutation in a Chinese family”
por: Wang, Jinling, et al.
Publicado: (2020)

Role of matrix metalloproteases 1/3 gene polymorphisms in patients with rotator cuff tear
por: Miao, Kaisong, et al.
Publicado: (2019)

Mitochondrial tRNA mutations in Chinese children with tic disorders
por: Jiang, Peifang, et al.
Publicado: (2020)

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes
por: Button, Emily L., et al.
Publicado: (2022)

Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome
por: Kapuganti, Ramani Shyam, et al.
Publicado: (2023)

hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang
por: Mulnix, Richard E, et al.
Publicado: (2013)

441 Cutaneous findings in COVID-19 patients hospitalized at a large urban academic medical center
por: Chand, S., et al.
Publicado: (2021)

461 A review of cutaneous lymphoma outcomes during COVID-19 pandemic at Columbia University
por: Garcia-Saleem, T., et al.
Publicado: (2021)

433 Increased risk of hospital acquired sacral pressure injuries in COVID-19 patients
por: Narang, J., et al.
Publicado: (2021)

Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits
por: Horn, Denise, et al.
Publicado: (2010)

Indirect Decompression Failure After Lateral Lumbar Interbody Fusion—Reported Failures and Predictive Factors: Systematic Review
por: Kirnaz, Sertac, et al.
Publicado: (2020)

Molecular Spectrum of Autosomal Dominant Hypercholesterolemia in France
por: Marduel, Marie, et al.
Publicado: (2010)

A Rare Novel Deletion of the Tyrosine Hydroxylase Gene in Parkinson Disease
por: Bademci, Güney, et al.
Publicado: (2010)

Evaluation of Germline BMP4 Mutation as a Cause of Colorectal Cancer
por: Lubbe, Steven J, et al.
Publicado: (2011)

Plectin Deficiency Leads to Both Muscular Dystrophy and Pyloric Atresia in Epidermolysis Bullosa Simplex
por: Natsuga, Ken, et al.
Publicado: (2010)

Mutations and Deletions in PCDH19 Account for Various Familial or Isolated Epilepsies in Females
por: Depienne, Christel, et al.
Publicado: (2011)

Mutations in LAMB2 causing a severe form of synaptic congenital myasthenic syndrome
por: Maselli, R A, et al.
Publicado: (2009)

A Novel Mutation in CRYBB1 Associated with Congenital Cataract-Microcornea Syndrome: The p.Ser129Arg Mutation Destabilizes the βB1/βA3-crystallin Heteromer But Not the βB1-crystallin Homomer
por: Wang, Kai Jie, et al.
Publicado: (2011)

Clinical and genetic spectrum of Birt–Hogg–Dubé syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature
por: Kunogi, Makiko, et al.
Publicado: (2010)

Lynch Syndrome-associated Mutations in MSH2 Alter DNA Repair and Checkpoint Response Functions In Vivo
por: Mastrocola, Adam S, et al.
Publicado: (2010)

Genetic Etiology of Parkinson Disease Associated with Mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 Genes: A Mutation Update
por: Nuytemans, Karen, et al.
Publicado: (2010)

Cerebral Arterial Stenoses and Stroke: Novel Features of Aicardi-Goutières Syndrome Caused by the Arg164X Mutation in SAMHD1 Are Associated with Altered Cytokine Expression
por: Thiele, Holger, et al.
Publicado: (2010)

A Novel CRYGD Mutation (p.Trp43Arg) Causing Autosomal Dominant Congenital Cataract in a Chinese Family
por: Wang, Binbin, et al.
Publicado: (2011)

Mutation Spectrum of EYS in Spanish Patients with Autosomal Recessive Retinitis Pigmentosa
por: Barragán, Isabel, et al.
Publicado: (2010)

A Novel Germline CDKN1B Mutation Causing Multiple Endocrine Tumors: Clinical, Genetic and Functional Characterization
por: Molatore, Sara, et al.
Publicado: (2010)

Adenine DNA Glycosylase Activity of 14 Human MutY Homolog (MUTYH) Variant Proteins Found in Patients with Colorectal Polyposis and Cancer
por: Goto, Masanori, et al.
Publicado: (2010)

Evaluating Self-declared Ancestry of U.S. Americans with Autosomal, Y-chromosomal and Mitochondrial DNA
por: Lao, Oscar, et al.
Publicado: (2010)

Legius Syndrome in Fourteen Families
por: Denayer, Ellen, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_qecmka3bfisj9v6i48l0cufgss