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Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users
OBJECTIVE: In this retrospective observational study, we evaluated awareness among patients using bisphosphonates (BPs) regarding the risk of developing medication-related osteonecrosis of the jaw (MRONJ) and whether they received appropriate dental screening and treatment prior to commencing medica...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493245/ https://www.ncbi.nlm.nih.gov/pubmed/32924697 http://dx.doi.org/10.1177/0300060520955066 |
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author | El-Ma’aita, Ahmad Da’as, Noor Al-Hattab, Mais Hassona, Yazan Al-Rabab’ah, Mohammad Al-Kayed, Mohammad-Awni |
author_facet | El-Ma’aita, Ahmad Da’as, Noor Al-Hattab, Mais Hassona, Yazan Al-Rabab’ah, Mohammad Al-Kayed, Mohammad-Awni |
author_sort | El-Ma’aita, Ahmad |
collection | PubMed |
description | OBJECTIVE: In this retrospective observational study, we evaluated awareness among patients using bisphosphonates (BPs) regarding the risk of developing medication-related osteonecrosis of the jaw (MRONJ) and whether they received appropriate dental screening and treatment prior to commencing medication. METHODS: Patients using BPs who attended the endodontics clinic at Jordan University Hospital in 2019 were interviewed using a pre-designed questionnaire. Data were analysed using descriptive statistics and chi-squared tests. RESULTS: In total, 110 patients were interviewed (84 women, 26 men; age 40–78 years). A total of 94 patients were using oral BP and 16 received intravenous (IV) BP. We found that only 12.4% of participants were aware about the risk of MRONJ following BP use, and only one third of them has received information from their prescribing physicians. In total, 5% of participants were referred to a dentist for screening prior to initiating BP treatment. Patients receiving IV BP and those with a university-level education had better awareness about the risk of MRONJ than oral BP users and those with a high school education level. CONCLUSION: Patients’ awareness about MRONJ risk was low in our population. Better patient education and collaboration among physicians and dentists are needed prior to starting BP treatment. |
format | Online Article Text |
id | pubmed-7493245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-74932452020-09-23 Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users El-Ma’aita, Ahmad Da’as, Noor Al-Hattab, Mais Hassona, Yazan Al-Rabab’ah, Mohammad Al-Kayed, Mohammad-Awni J Int Med Res Pre-Clinical Research Report OBJECTIVE: In this retrospective observational study, we evaluated awareness among patients using bisphosphonates (BPs) regarding the risk of developing medication-related osteonecrosis of the jaw (MRONJ) and whether they received appropriate dental screening and treatment prior to commencing medication. METHODS: Patients using BPs who attended the endodontics clinic at Jordan University Hospital in 2019 were interviewed using a pre-designed questionnaire. Data were analysed using descriptive statistics and chi-squared tests. RESULTS: In total, 110 patients were interviewed (84 women, 26 men; age 40–78 years). A total of 94 patients were using oral BP and 16 received intravenous (IV) BP. We found that only 12.4% of participants were aware about the risk of MRONJ following BP use, and only one third of them has received information from their prescribing physicians. In total, 5% of participants were referred to a dentist for screening prior to initiating BP treatment. Patients receiving IV BP and those with a university-level education had better awareness about the risk of MRONJ than oral BP users and those with a high school education level. CONCLUSION: Patients’ awareness about MRONJ risk was low in our population. Better patient education and collaboration among physicians and dentists are needed prior to starting BP treatment. SAGE Publications 2020-09-14 /pmc/articles/PMC7493245/ /pubmed/32924697 http://dx.doi.org/10.1177/0300060520955066 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Pre-Clinical Research Report El-Ma’aita, Ahmad Da’as, Noor Al-Hattab, Mais Hassona, Yazan Al-Rabab’ah, Mohammad Al-Kayed, Mohammad-Awni Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title | Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title_full | Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title_fullStr | Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title_full_unstemmed | Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title_short | Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
title_sort | awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users |
topic | Pre-Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493245/ https://www.ncbi.nlm.nih.gov/pubmed/32924697 http://dx.doi.org/10.1177/0300060520955066 |
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