Comparison of 4 Screening Methods for Detecting Fluoropyrimidine Toxicity Risk: Identification of the Most Effective, Cost-Efficient Method to Save Lives

BACKGROUND: Fluoropyrimidines (FPs) carry around 20% risk of G3-5 toxicity and 0.2-1% risk of death, due to dihydropyrimidine dehydrogenase (DPD) deficiency. Several screening approaches exist for predicting toxicity, however there is ongoing debate over which method is best. This study compares 4 s...

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Detalles Bibliográficos
Autores principales: Capitain, Olivier, Seegers, Valérie, Metges, Jean-Philippe, Faroux, Roger, Stampfli, Claire, Ferec, Marc, Budnik, Tamara Matysiak, Senellart, Hélène, Rossi, Valérie, Blouin, Nadège, Dauvé, Jonathan, Campone, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493257/
https://www.ncbi.nlm.nih.gov/pubmed/32973417
http://dx.doi.org/10.1177/1559325820951367

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