Cargando…
Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation
Alzheimer’s disease (AD) is a neurodegenerative disease that leads to progressive loss of memory and dementia. The pathological hallmarks of AD include extracellular accumulation of amyloid-β peptides forming senile plaques and intracellular accumulation of Tau oligomers and filamentous species. Tau...
Autores principales: | Chidambaram, Hariharakrishnan, Das, Rashmi, Chinnathambi, Subashchandrabose |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493323/ https://www.ncbi.nlm.nih.gov/pubmed/32944223 http://dx.doi.org/10.1186/s13578-020-00474-4 |
Ejemplares similares
-
G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2021) -
Basic Limonoid modulates Chaperone-mediated Proteostasis and dissolve Tau fibrils
por: Gorantla, Nalini Vijay, et al.
Publicado: (2020) -
EGCG impedes human Tau aggregation and interacts with Tau
por: Sonawane, Shweta Kishor, et al.
Publicado: (2020) -
Microglia degrade Tau oligomers deposit via purinergic P2Y12-associated podosome and filopodia formation and induce chemotaxis
por: Chinnathambi, Subashchandrabose, et al.
Publicado: (2023) -
Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
por: Das, Rashmi, et al.
Publicado: (2020)