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Resolution of Racemic Guaifenesin Applying a Coupled Preferential Crystallization-Selective Dissolution Process: Rational Process Development
[Image: see text] Preferential crystallization is a cost efficient method to provide pure enantiomers from a racemic mixture of a conglomerate forming system. Exploiting small amounts of pure crystals of both enantiomers, several batch or continuous processes were developed, capable of providing bot...
Autores principales: | Temmel, Erik, Eicke, Matthias J., Cascella, Francesca, Seidel-Morgenstern, Andreas, Lorenz, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493326/ https://www.ncbi.nlm.nih.gov/pubmed/32952448 http://dx.doi.org/10.1021/acs.cgd.8b01660 |
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