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Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)
BACKGROUND: Early and appropriate antibiotic dosing is associated with improved clinical outcomes in critically ill patients, yet target attainment remains a challenge. Traditional antibiotic dosing is not suitable in critically ill patients, since these patients undergo physiological alterations th...
Autores principales: | Abdulla, Alan, Dijkstra, Annemieke, Hunfeld, Nicole G. M., Endeman, Henrik, Bahmany, Soma, Ewoldt, Tim M. J., Muller, Anouk E., van Gelder, Teun, Gommers, Diederik, Koch, Birgit C. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493358/ https://www.ncbi.nlm.nih.gov/pubmed/32933574 http://dx.doi.org/10.1186/s13054-020-03272-z |
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