Plasma-based longitudinal mutation monitoring as a potential predictor of disease progression in subjects with adenocarcinoma in advanced non-small cell lung cancer

BACKGROUND: Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung cancer (NSCLC). METHODS: Baseline tumor tissue (n = 47) and longitudinal plasma (n ...

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Detalles Bibliográficos
Autores principales: Jiang, John, Adams, Hans-Peter, Lange, Maria, Siemann, Sandra, Feldkamp, Mirjam, McNamara, Sylvie, Froehler, Sebastian, Yaung, Stephanie J., Yao, Lijing, Balasubramanyam, Aarthi, Tikoo, Nalin, Ju, Christine, Achenbach, H. Jost, Krügel, Rainer, Palma, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493404/
https://www.ncbi.nlm.nih.gov/pubmed/32933495
http://dx.doi.org/10.1186/s12885-020-07340-z

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