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Quantitative systems pharmacology and the personalized drug–microbiota–diet axis

Precision medicine is an emerging paradigm that aims at maximizing the benefits and minimizing the adverse effects of drugs. Realistic mechanistic models are needed to understand and limit heterogeneity in drug responses. While pharmacokinetic models describe in detail a drug's absorption and m...

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Detalles Bibliográficos
Autores principales: Thiele, Ines, Clancy, Catherine M., Heinken, Almut, Fleming, Ronan M.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493425/
https://www.ncbi.nlm.nih.gov/pubmed/32984662
http://dx.doi.org/10.1016/j.coisb.2017.06.001