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Tristetraprolin Overexpression in Non-hematopoietic Cells Protects Against Acute Lung Injury in Mice

Tristetraprolin (TTP) is a mRNA binding protein that binds to adenylate-uridylate-rich elements within the 3′ untranslated regions of certain transcripts, such as tumor necrosis factor (Tnf) mRNA, and increases their rate of decay. Modulation of TTP expression is implicated in inflammation; however,...

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Detalles Bibliográficos
Autores principales: Choudhary, Ishita, Vo, Thao, Bathula, Chandra S., Lamichhane, Richa, Lewis, Brandon W., Looper, Jayme, Jeyaseelan, Samithamby, Blackshear, Perry J., Saini, Yogesh, Patial, Sonika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493631/
https://www.ncbi.nlm.nih.gov/pubmed/32983182
http://dx.doi.org/10.3389/fimmu.2020.02164