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Tristetraprolin Overexpression in Non-hematopoietic Cells Protects Against Acute Lung Injury in Mice
Tristetraprolin (TTP) is a mRNA binding protein that binds to adenylate-uridylate-rich elements within the 3′ untranslated regions of certain transcripts, such as tumor necrosis factor (Tnf) mRNA, and increases their rate of decay. Modulation of TTP expression is implicated in inflammation; however,...
Autores principales: | Choudhary, Ishita, Vo, Thao, Bathula, Chandra S., Lamichhane, Richa, Lewis, Brandon W., Looper, Jayme, Jeyaseelan, Samithamby, Blackshear, Perry J., Saini, Yogesh, Patial, Sonika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493631/ https://www.ncbi.nlm.nih.gov/pubmed/32983182 http://dx.doi.org/10.3389/fimmu.2020.02164 |
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