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Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis

INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel disease (IBD) patients, especially those on immunosuppressive therapies or with active disease. There are limited reports describing the clinical features of COVI...

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Autores principales: Garcia, Karoline Soares, Moutinho, Bruna Damásio, de Azevedo, Matheus Freitas Cardoso, Queiroz, Natalia Sousa Freitas, Milani, Luciane Reis, Sanches, Lucas Navarro, Barros, Luisa Leite, Oba, Jane, Carlos, Alexandre de Sousa, Damião, Aderson Omar Mourão Cintra, Sipahi, Aytan Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493790/
https://www.ncbi.nlm.nih.gov/pubmed/32984404
http://dx.doi.org/10.1159/000508161
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author Garcia, Karoline Soares
Moutinho, Bruna Damásio
de Azevedo, Matheus Freitas Cardoso
Queiroz, Natalia Sousa Freitas
Milani, Luciane Reis
Sanches, Lucas Navarro
Barros, Luisa Leite
Oba, Jane
Carlos, Alexandre de Sousa
Damião, Aderson Omar Mourão Cintra
Sipahi, Aytan Miranda
author_facet Garcia, Karoline Soares
Moutinho, Bruna Damásio
de Azevedo, Matheus Freitas Cardoso
Queiroz, Natalia Sousa Freitas
Milani, Luciane Reis
Sanches, Lucas Navarro
Barros, Luisa Leite
Oba, Jane
Carlos, Alexandre de Sousa
Damião, Aderson Omar Mourão Cintra
Sipahi, Aytan Miranda
author_sort Garcia, Karoline Soares
collection PubMed
description INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel disease (IBD) patients, especially those on immunosuppressive therapies or with active disease. There are limited reports describing the clinical features of COVID-19 in an IBD population, and the impact of immunosuppression on the severity of the infection remains unclear. CASE REPORT: A 33-year-old female patient with a long history of ulcerative colitis, poorly controlled, was admitted with COVID-19 a few days after being discharged from the hospital for treatment of acute severe ulcerative colitis. High-risk factors for COVID-19 complications, i.e., high-dose steroids (40 mg prednisone) and severe active disease, were present at admission. Despite the development of extensive pulmonary involvement, the patient had a favorable outcome. DISCUSSION: Management of IBD patients during the COVID-19 pandemic has been challenging. Measures to minimize the potential risk of SARS-CoV-2 infection, including strict social distancing and self-isolation, in the IBD population have been recommended, especially for high-risk patients. Although steroid tapering and persistence of biologics are advised by professional groups, the best treatment strategy for IBD patients presenting a flare during the outbreak has yet to be defined.
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spelling pubmed-74937902020-09-25 Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis Garcia, Karoline Soares Moutinho, Bruna Damásio de Azevedo, Matheus Freitas Cardoso Queiroz, Natalia Sousa Freitas Milani, Luciane Reis Sanches, Lucas Navarro Barros, Luisa Leite Oba, Jane Carlos, Alexandre de Sousa Damião, Aderson Omar Mourão Cintra Sipahi, Aytan Miranda Inflamm Intest Dis Case Report INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel disease (IBD) patients, especially those on immunosuppressive therapies or with active disease. There are limited reports describing the clinical features of COVID-19 in an IBD population, and the impact of immunosuppression on the severity of the infection remains unclear. CASE REPORT: A 33-year-old female patient with a long history of ulcerative colitis, poorly controlled, was admitted with COVID-19 a few days after being discharged from the hospital for treatment of acute severe ulcerative colitis. High-risk factors for COVID-19 complications, i.e., high-dose steroids (40 mg prednisone) and severe active disease, were present at admission. Despite the development of extensive pulmonary involvement, the patient had a favorable outcome. DISCUSSION: Management of IBD patients during the COVID-19 pandemic has been challenging. Measures to minimize the potential risk of SARS-CoV-2 infection, including strict social distancing and self-isolation, in the IBD population have been recommended, especially for high-risk patients. Although steroid tapering and persistence of biologics are advised by professional groups, the best treatment strategy for IBD patients presenting a flare during the outbreak has yet to be defined. S. Karger AG 2020-06 2020-05-06 /pmc/articles/PMC7493790/ /pubmed/32984404 http://dx.doi.org/10.1159/000508161 Text en Copyright © 2020 by S. Karger AG, Basel
spellingShingle Case Report
Garcia, Karoline Soares
Moutinho, Bruna Damásio
de Azevedo, Matheus Freitas Cardoso
Queiroz, Natalia Sousa Freitas
Milani, Luciane Reis
Sanches, Lucas Navarro
Barros, Luisa Leite
Oba, Jane
Carlos, Alexandre de Sousa
Damião, Aderson Omar Mourão Cintra
Sipahi, Aytan Miranda
Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title_full Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title_fullStr Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title_full_unstemmed Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title_short Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis
title_sort recovery from covid-19 pneumonia in a patient with acute severe colitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493790/
https://www.ncbi.nlm.nih.gov/pubmed/32984404
http://dx.doi.org/10.1159/000508161
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