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Quantification of Factor H Mediated Self vs. Non-self Discrimination by Mathematical Modeling
The complement system is part of the innate immune system and plays an important role in the host defense against infectious pathogens. One of the main effects is the opsonization of foreign invaders and subsequent uptake by phagocytosis. Due to the continuous default basal level of active complemen...
Autores principales: | Tille, Alexander, Lehnert, Teresa, Zipfel, Peter F., Figge, Marc Thilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493836/ https://www.ncbi.nlm.nih.gov/pubmed/33013842 http://dx.doi.org/10.3389/fimmu.2020.01911 |
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