PRV UL13 inhibits cGAS–STING-mediated IFN-β production by phosphorylating IRF3

Cyclic GMP-AMP (cGAMP) synthase (cGAS) is an intracellular sensor of cytoplasmic viral DNA created during virus infection, which subsequently activates the stimulator of interferon gene (STING)-dependent type I interferon response to eliminate pathogens. In contrast, viruses have developed different...

Descripción completa

Detalles Bibliográficos
Autores principales: Bo, Zongyi, Miao, Yurun, Xi, Rui, Zhong, Qiuping, Bao, Chenyi, Chen, Huan, Sun, Liumei, Qian, Yingjuan, Jung, Yong-Sam, Dai, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493860/
https://www.ncbi.nlm.nih.gov/pubmed/32933581
http://dx.doi.org/10.1186/s13567-020-00843-4

Ejemplares similares

Ejemplares similares