Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance via PTEN-mediated crosstalk between the PI3K/Akt and Erk/MAPKs signaling pathways in the skeletal muscles of db/db mice

BACKGROUND: Globally, 1 in 11 adults have diabetes mellitus, and 90% of the cases are type 2 diabetes mellitus. Insulin resistance is a central defect in type 2 diabetes mellitus, and although multiple drugs have been developed to ameliorate insulin resistance, the limitations and accompanying side...

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Detalles Bibliográficos
Autores principales: Chen, Guang, Fan, Xiao-yan, Zheng, Xiao-peng, Jin, Yue-lei, Liu, Ying, Liu, Shuang-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493876/
https://www.ncbi.nlm.nih.gov/pubmed/32938466
http://dx.doi.org/10.1186/s13287-020-01865-7

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