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Elevated IL-6R on CD4(+) T cells promotes IL-6 driven Th17 cell responses in patients with T1R leprosy reactions
Th17 cells play vital role during pathogenesis of leprosy reactions. Previously, we have reported that IL-23 is involved in Th17 cells differentiation. Subsequently, our group also showed that IL-6 induces Th17 cell differentiation along with TGF-β in leprosy reactions. Here, we next asked the quest...
Autores principales: | Saini, Chaman, Srivastava, Rupesh K., Tarique, Mohd., Kurra, Santosh, Khanna, Neena, Ramesh, V., Sharma, Alpana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493991/ https://www.ncbi.nlm.nih.gov/pubmed/32934336 http://dx.doi.org/10.1038/s41598-020-72148-7 |
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