Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption

Osteoprotegerin (OPG) inhibits the ability of receptor activator of nuclear factor κB (NF-κB) ligand (RANKL) to stimulate the differentiation, activity, and survival of bone-resorbing osteoclasts. Genetic studies in mice show that osteocytes are an important source of RANKL, but the cellular sources...

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Detalles Bibliográficos
Autores principales: Cawley, Keisha M., Bustamante-Gomez, Nancy Cecile, Guha, Anveshi G., MacLeod, Ryan S., Xiong, Jinhu, Gubrij, Igor, Liu, Yu, Mulkey, Robin, Palmieri, Michela, Thostenson, Jeff D., Goellner, Joseph J., O’Brien, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493998/
https://www.ncbi.nlm.nih.gov/pubmed/32905775
http://dx.doi.org/10.1016/j.celrep.2020.108052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493998/
https://www.ncbi.nlm.nih.gov/pubmed/32905775
http://dx.doi.org/10.1016/j.celrep.2020.108052

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