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Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration

Zebrafish regenerate heart muscle through division of pre-existing cardiomyocytes. To discover underlying regulation, we assess transcriptome datasets for dynamic gene networks during heart regeneration and identify suppression of genes associated with the transcription factor Tp53. Cardiac damage l...

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Detalles Bibliográficos
Autores principales:	Shoffner, Adam, Cigliola, Valentina, Lee, Nutishia, Ou, Jianhong, Poss, Kenneth D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494019/ https://www.ncbi.nlm.nih.gov/pubmed/32877671 http://dx.doi.org/10.1016/j.celrep.2020.108089

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