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Post-exposure prophylaxis (PEP) efficacy of rifampin, rifapentine, moxifloxacin, minocycline, and clarithromycin in a susceptible-subclinical model of leprosy

BACKGROUND: Subclinical infection with Mycobacterium leprae is one potential source of leprosy transmission, and post-exposure prophylaxis (PEP) regimens have been proposed to control this source. Because PEP trials require considerable investment, we applied a sensitive variation of the kinetic mou...

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Detalles Bibliográficos
Autores principales: Lenz, Shannon M., Collins, Jaymes H., Ray, Nashone A., Hagge, Deanna A., Lahiri, Ramanuj, Adams, Linda B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494095/
https://www.ncbi.nlm.nih.gov/pubmed/32936818
http://dx.doi.org/10.1371/journal.pntd.0008583

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