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Post-exposure prophylaxis (PEP) efficacy of rifampin, rifapentine, moxifloxacin, minocycline, and clarithromycin in a susceptible-subclinical model of leprosy
BACKGROUND: Subclinical infection with Mycobacterium leprae is one potential source of leprosy transmission, and post-exposure prophylaxis (PEP) regimens have been proposed to control this source. Because PEP trials require considerable investment, we applied a sensitive variation of the kinetic mou...
Autores principales: | Lenz, Shannon M., Collins, Jaymes H., Ray, Nashone A., Hagge, Deanna A., Lahiri, Ramanuj, Adams, Linda B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494095/ https://www.ncbi.nlm.nih.gov/pubmed/32936818 http://dx.doi.org/10.1371/journal.pntd.0008583 |
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