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Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494185/ https://www.ncbi.nlm.nih.gov/pubmed/32974581 http://dx.doi.org/10.1099/acmi.0.000123 |
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author | Purwanto, Diana Shintawati Loho, Tonny Tafroji, Wisnu Mangunatmadja, Irawan Immanuel, Suzanna Timan, Ina Susianti Yusra, Yusra Safari, Dodi |
author_facet | Purwanto, Diana Shintawati Loho, Tonny Tafroji, Wisnu Mangunatmadja, Irawan Immanuel, Suzanna Timan, Ina Susianti Yusra, Yusra Safari, Dodi |
author_sort | Purwanto, Diana Shintawati |
collection | PubMed |
description | CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia. |
format | Online Article Text |
id | pubmed-7494185 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Microbiology Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-74941852020-09-23 Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia Purwanto, Diana Shintawati Loho, Tonny Tafroji, Wisnu Mangunatmadja, Irawan Immanuel, Suzanna Timan, Ina Susianti Yusra, Yusra Safari, Dodi Access Microbiol Case Report CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia. Microbiology Society 2020-03-26 /pmc/articles/PMC7494185/ /pubmed/32974581 http://dx.doi.org/10.1099/acmi.0.000123 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License. |
spellingShingle | Case Report Purwanto, Diana Shintawati Loho, Tonny Tafroji, Wisnu Mangunatmadja, Irawan Immanuel, Suzanna Timan, Ina Susianti Yusra, Yusra Safari, Dodi Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title | Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title_full | Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title_fullStr | Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title_full_unstemmed | Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title_short | Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia |
title_sort | isolation and identification of streptococcus pneumoniae serotype 6b from a patient with bacterial meningitis infection in jakarta, indonesia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494185/ https://www.ncbi.nlm.nih.gov/pubmed/32974581 http://dx.doi.org/10.1099/acmi.0.000123 |
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