Cargando…

Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia

CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. p...

Descripción completa

Detalles Bibliográficos
Autores principales: Purwanto, Diana Shintawati, Loho, Tonny, Tafroji, Wisnu, Mangunatmadja, Irawan, Immanuel, Suzanna, Timan, Ina Susianti, Yusra, Yusra, Safari, Dodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494185/
https://www.ncbi.nlm.nih.gov/pubmed/32974581
http://dx.doi.org/10.1099/acmi.0.000123
_version_ 1783582699030577152
author Purwanto, Diana Shintawati
Loho, Tonny
Tafroji, Wisnu
Mangunatmadja, Irawan
Immanuel, Suzanna
Timan, Ina Susianti
Yusra, Yusra
Safari, Dodi
author_facet Purwanto, Diana Shintawati
Loho, Tonny
Tafroji, Wisnu
Mangunatmadja, Irawan
Immanuel, Suzanna
Timan, Ina Susianti
Yusra, Yusra
Safari, Dodi
author_sort Purwanto, Diana Shintawati
collection PubMed
description CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia.
format Online
Article
Text
id pubmed-7494185
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Microbiology Society
record_format MEDLINE/PubMed
spelling pubmed-74941852020-09-23 Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia Purwanto, Diana Shintawati Loho, Tonny Tafroji, Wisnu Mangunatmadja, Irawan Immanuel, Suzanna Timan, Ina Susianti Yusra, Yusra Safari, Dodi Access Microbiol Case Report CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia. Microbiology Society 2020-03-26 /pmc/articles/PMC7494185/ /pubmed/32974581 http://dx.doi.org/10.1099/acmi.0.000123 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Case Report
Purwanto, Diana Shintawati
Loho, Tonny
Tafroji, Wisnu
Mangunatmadja, Irawan
Immanuel, Suzanna
Timan, Ina Susianti
Yusra, Yusra
Safari, Dodi
Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title_full Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title_fullStr Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title_full_unstemmed Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title_short Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
title_sort isolation and identification of streptococcus pneumoniae serotype 6b from a patient with bacterial meningitis infection in jakarta, indonesia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494185/
https://www.ncbi.nlm.nih.gov/pubmed/32974581
http://dx.doi.org/10.1099/acmi.0.000123
work_keys_str_mv AT purwantodianashintawati isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT lohotonny isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT tafrojiwisnu isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT mangunatmadjairawan isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT immanuelsuzanna isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT timaninasusianti isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT yusrayusra isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia
AT safaridodi isolationandidentificationofstreptococcuspneumoniaeserotype6bfromapatientwithbacterialmeningitisinfectioninjakartaindonesia