Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada

We identified and characterized a genome of the multi-drug-resistant Bacteroides genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a...

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Autores principales: Graham, Christopher, Eshaghi, Alireza, Sarabia, Alicia, Zittermann, Sandra, Stapleton, Patrick, Kus, Julianne V., Patel, Samir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494187/
https://www.ncbi.nlm.nih.gov/pubmed/32974576
http://dx.doi.org/10.1099/acmi.0.000111
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author Graham, Christopher
Eshaghi, Alireza
Sarabia, Alicia
Zittermann, Sandra
Stapleton, Patrick
Kus, Julianne V.
Patel, Samir N.
author_facet Graham, Christopher
Eshaghi, Alireza
Sarabia, Alicia
Zittermann, Sandra
Stapleton, Patrick
Kus, Julianne V.
Patel, Samir N.
author_sort Graham, Christopher
collection PubMed
description We identified and characterized a genome of the multi-drug-resistant Bacteroides genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a plasmid containing the nimE gene, which has been shown to be associated with metronidazole resistance. The study highlights the importance of being vigilant in suspecting antimicrobial drug resistance when a patient is not improving on therapy.
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spelling pubmed-74941872020-09-23 Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada Graham, Christopher Eshaghi, Alireza Sarabia, Alicia Zittermann, Sandra Stapleton, Patrick Kus, Julianne V. Patel, Samir N. Access Microbiol Case Report We identified and characterized a genome of the multi-drug-resistant Bacteroides genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a plasmid containing the nimE gene, which has been shown to be associated with metronidazole resistance. The study highlights the importance of being vigilant in suspecting antimicrobial drug resistance when a patient is not improving on therapy. Microbiology Society 2020-02-26 /pmc/articles/PMC7494187/ /pubmed/32974576 http://dx.doi.org/10.1099/acmi.0.000111 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Case Report
Graham, Christopher
Eshaghi, Alireza
Sarabia, Alicia
Zittermann, Sandra
Stapleton, Patrick
Kus, Julianne V.
Patel, Samir N.
Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title_full Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title_fullStr Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title_full_unstemmed Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title_short Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada
title_sort identification and characterization of invasive multi-drug-resistant (mdr) bacteroides genomospecies in canada
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494187/
https://www.ncbi.nlm.nih.gov/pubmed/32974576
http://dx.doi.org/10.1099/acmi.0.000111
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