HSPA12B Secreted by Tumor-Associated Endothelial Cells Might Induce M2 Polarization of Macrophages via Activating PI3K/Akt/mTOR Signaling

PURPOSE: The intratumoral microenvironment of head and neck squamous cell carcinoma (HNSC) is highly immunosuppressive. In this study, we explored the potential functional role of HSPA12B secreted by tumor-associated endothelial cells (TECs) in M2 polarization of macrophages. MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Zhou, Jingjie, Zhang, Aiping, Fan, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494226/
https://www.ncbi.nlm.nih.gov/pubmed/32982299
http://dx.doi.org/10.2147/OTT.S254985

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