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The NRF2/KEAP1 Pathway Modulates Nasopharyngeal Carcinoma Cell Radiosensitivity via ROS Elimination

PURPOSE: Radioresistance is a vital obstacle for the prognosis of human nasopharyngeal carcinoma (NPC), but the underlying mechanism is still unknown. Here, we explored the role of the NRF2/KEAP1 pathway in radioresistance of NPC cell lines. MATERIALS AND METHODS: We selected NPC cell lines CNE-1 an...

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Detalles Bibliográficos
Autores principales: Zhou, Jieyu, Ding, Jiping, Ma, Xingkai, Zhang, Meichao, Huo, Zirong, Yao, Yuan, Li, Dong, Wang, Zhentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494231/
https://www.ncbi.nlm.nih.gov/pubmed/32982300
http://dx.doi.org/10.2147/OTT.S260169