Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

Limited knowledge is available on the relationship between antigen-specific immune responses and COVID-19 disease severity. We completed a combined examination of all three branches of adaptive immunity at the level of SARS-CoV-2-specific CD4(+) and CD8(+) T cell and neutralizing antibody responses...

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Detalles Bibliográficos
Autores principales: Rydyznski Moderbacher, Carolyn, Ramirez, Sydney I., Dan, Jennifer M., Grifoni, Alba, Hastie, Kathryn M., Weiskopf, Daniela, Belanger, Simon, Abbott, Robert K., Kim, Christina, Choi, Jinyong, Kato, Yu, Crotty, Eleanor G., Kim, Cheryl, Rawlings, Stephen A., Mateus, Jose, Tse, Long Ping Victor, Frazier, April, Baric, Ralph, Peters, Bjoern, Greenbaum, Jason, Ollmann Saphire, Erica, Smith, Davey M., Sette, Alessandro, Crotty, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494270/
https://www.ncbi.nlm.nih.gov/pubmed/33010815
http://dx.doi.org/10.1016/j.cell.2020.09.038

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