A V(H)1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite

An oligomannose patch around the V3 base of HIV-1 envelope glycoprotein (Env) is recognized by multiple classes of broadly neutralizing antibodies (bNAbs). Here, we investigated the bNAb response to the V3 glycan supersite in an HIV-1–infected Chinese donor by Env-specific single B cell sorting, str...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Sonu, Ju, Bin, Shapero, Benjamin, Lin, Xiaohe, Ren, Li, Zhang, Lei, Li, Dan, Zhou, Zehua, Feng, Yi, Sou, Cindy, Mann, Colin J., Hao, Yanling, Sarkar, Anita, Hou, Jiali, Nunnally, Christian, Hong, Kunxue, Wang, Shuo, Ge, Xiangyang, Su, Bin, Landais, Elise, Sok, Devin, Zwick, Michael B., He, Linling, Zhu, Jiang, Wilson, Ian A., Shao, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494343/
https://www.ncbi.nlm.nih.gov/pubmed/32938661
http://dx.doi.org/10.1126/sciadv.abb1328

Ejemplares similares

Ejemplares similares